Unable to start Outlook after upgrading to Windows 10

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Issue

After upgrading to Windows 10, Outlook 2013 might fail to open, and you receive this error:

Cannot start Microsoft Outlook. Cannot open the Outlook window. The set of folders cannot be opened. File access is denied. You do not have the permission required to access the file C:\Users\<username>\Documents\Outlook Files\filename.pst.

Cause

This issue might happen when you’re prompted to login to Windows with a Microsoft Account, (Outlook.com, Live, Hotmail, or MSN), instead of your local account. In that case the permission changes were not applied properly.

We’re investigating to resolve the issue, but you can use the workaround below in the meanwhile:

Workaround

To regain access to the PST file, reset permissions using the steps below:

  1. Right click the Start button and select File Explorer.
  2. Browse to the file location as indicated in the error. For example, C:\Users\<username>\Documents\Outlook Files\filename.pst.
  3. Right click the file and choose Properties.
  4. Select the Security tab.
  5. Select the Edit button.
  6. Select your user account.
  7. Select Full control permission.
  8. Choose OK until all dialogs boxes are closed.
  9. Repeat the same steps for Administrators and System also, to have Full Control permissions.
  10. Restart Outlook.

If the issue  persists there might be an issue with  system registry  settings , configuration files or temporary files.

It is strongly recommended to have check on your computer by the technical support member,

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Unable to access PST File or start Outlook after upgrading to Windows 10